| R64 | Lauren Long (WLU) def. No Player (--) by default |
| Grace Lorenz (WLU) def. Stephanie Untermeyer (SIT) 6-0, 6-3 |
| Elaine Qian (CMU) def. Haley Stoltz (WLU) 6-4, 6-3 |
| Divya Venkatarama (CMU) def. Margaret Carlton (WLU) 6-2, 6-0 |
| Gabi Moss (WLU) def. Jacey Copeland (UMW) 6-1, 6-1 |
| Eda Mjekiqi (SWA) def. Riho Iijima (WLU) 6-2, 6-3 |
| Annie Jennings (WLU) def. Ainika Hou (CMU) 6-2, 6-0 |
| Izzy Koziol (WLU) def. Rachael Fitzgerald (HAV) 6-4, 6-0 |
| R32 | Lauren Long (WLU) def. Anna Chow (CMU) 6-3, 7-5 |
| Jay Xiao (JHU) def. Grace Lorenz (WLU) 7-5, 1-6, 1-0 (10-6) |
| Gabi Moss (WLU) def. Samantha Robertson (CNU) 6-1, 6-4 |
| Annie Jennings (WLU) def. Addison Felts (UMW) 6-1, 2-6, 1-0 (10-7) |
| Danna Taylor (CMU) def. Izzy Koziol (WLU) 6-1, 6-1 |
| R16 | Lauren Long (WLU) def. Kamila Wong (JHU) 6-3, 6-2 |
| Gabi Moss (WLU) def. Sophia Kim (JHU) 6-3, 6-1 |
| Sydney Langer (JHU) def. Annie Jennings (WLU) 6-1, 6-2 |
| QF | Lauren Long (WLU) def. Jay Xiao (JHU) 6-7 (2-7), 6-1, 1-0 (10-8) |
| Mary Beth Hurley (JHU) def. Gabi Moss (WLU) 6-3, 6-4 |
| SF | Divya Venkatarama (CMU) def. Lauren Long (WLU) 6-4, 3-6, 6-4 |
